SNRIs vs SSRIs

generally more weight neutral

less sexual side effects

not first line - try once pt failed an SSRI

Pristiq MDD

Menopause

Fibromyalgia

NOT effective for anxiety

Effexor

Avoid if pt has high BP

Avoid if pt is not good keeping taking meds in mind (consistency needed)

Cymbalta

Sedating

Weight neutral

Minimal sexual side effects

For comorbid pain (please note higher doses are needed for pain control)